EPX-55555-000 – 96-Well Hand-Held Magnetic Plate Washer and EPX480-20834-901 – MO Immune Monitoring 48Plex, 96 Tests

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Publicada25 sep 2026Cierre de ofertas28 sep 2026 · 13:00 (hora de UTC)

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NOTICE OF INTENT – SOLE SOURCE ACQUISITION Notice No.: 75N98026Q01254 The National Institutes of Health (NIH) intends to award a Firm-Fixed-Price Purchase Order to Thermo Fisher Scientific for the following products: EPX-55555-000 – 96-Well Hand-Held Magnetic Plate Washer EPX480-20834-901 – MO Immune Monitoring 48Plex, 96 Tests The Government intends to solicit from a single source in accordance with FAR 6.302-1, Only One Responsible Source and No Other Supplies or Services Will Satisfy Agency Requirements. DESCRIPTION OF REQUIREMENT The research project is investigating the effects of sarcoma cancers and autoimmune disease on ovarian function in humans. A principal objective of the research is to determine whether alterations in pro-inflammatory signaling are associated with impaired or altered ovarian function. The research requires measurement of concentrations of multiple soluble inflammatory markers in biological specimens, including blood and ovarian tissue. The requested ProcartaPlex MO Immune Monitoring 48Plex assay provides simultaneous measurement of 48 soluble immune-related markers using a multiplex bead-based assay platform. The requirement consists of the following: EPX480-20834-901 – MO Immune Monitoring 48Plex, 96 Tests, for multiplex measurement of the required 48 soluble immune and inflammatory markers; and EPX-55555-000 – 96-Well Hand-Held Magnetic Plate Washer, required to support the magnetic-bead assay processing and washing steps associated with the multiplex assay workflow. The requested supplies are necessary to complete the laboratory analysis of biological specimens already generated during the research study. JUSTIFICATION FOR SOLE-SOURCE ACQUISITION The requested ProcartaPlex assay is required because the research protocol calls for simultaneous measurement of a defined panel of 48 soluble immune and inflammatory markers from the study specimens. The assay provides the required multiplex capability and is configured to permit the research team to evaluate a broad panel of inflammatory biomarkers from limited biological sample volumes. The research involves specimens obtained from an animal study in which the animals have already been euthanized and the biological specimens have been collected. These specimens represent a finite research resource and cannot readily be recreated without repeating the underlying animal study. Failure to obtain and analyze the available specimens would prevent the investigators from completing the planned biomarker analysis and would materially limit the ability to compare the animal findings with the corresponding human research. The requested Thermo Fisher products are required to maintain consistency with the assay methodology, reagents, plate format, detection technology, and established laboratory procedures being used for this research. Substitution with a different assay platform would require development, validation, and/or re-optimization of an alternative 48-marker panel and cou

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